How much do you know about the Ellanse effect?
2026-09-03
The Ellanse effect can provide immediate volume and stimulate collagen production.
The CMC component of Ellanse helps to fill in volume right after the treatment.
The PCL component induces collagen production, allowing for changes in elasticity and volume over time.

Hello, this is Derna Clinic.
The reason for considering volume treatments may not simply be to look prettier. Many people start with the desire to regain the firmness of their original face instead of the sunken lines and sagging contours they see in the mirror.
It’s not just about temporary volume; it’s about a change where my skin produces collagen on its own and fills up. This is why many people are interested in the Ellanse effect. Today, I will explain Ellanse in detail.
Understanding the core principles of the Ellanse effect at a glance

In one sentence, Ellanse can be described as follows:
"A treatment that fills volume immediately while helping my skin to produce collagen on its own."
Let me explain a bit more. As we age, collagen in our skin gradually decreases. When collagen decreases, the skin sags, volume is lost, and wrinkles begin to form.
Ellanse fills in volume in these sunken and sagging areas while simultaneously stimulating collagen to be produced again within my skin. It’s not just about filling; it’s a method aimed at improving the skin.
Difference between Hyaluronic Acid Fillers and Ellanse Effect
Although Ellanse is a type of filler, it works differently. Hyaluronic acid fillers physically fill the space under the skin. Volume appears instantly upon injection, and over time, it is gradually absorbed and disappears.
Ellanse is a fourth-generation filler that takes it a step further. It has an immediate volume effect while also stimulating the skin to produce collagen through its collagen regeneration function.
Key Ingredients of the Ellanse Effect, CMC + PCL

The reason Ellanse can produce this dual effect is due to its two key ingredients: CMC (Carboxymethyl Cellulose) and PCL (Poly-caprolactone). Each of these plays a different role.
🟡From immediately after treatment to 2-4 weeks
The CMC component first fills in the volume. Thanks to this ingredient, you can feel volume changes immediately after the treatment. At the same time, it also plays a role in evenly distributing PCL micro-particles throughout the skin. Like planting seeds, it prepares for collagen to grow well.
🟡After 4 weeks
The PCL micro-particles begin to induce collagen production within the skin. Over time, CMC is gradually absorbed by the body, and the space it occupied is filled by collagen that my skin produces on its own. Even after all the micro-particles are absorbed, the collagen structure remains intact, allowing for long-lasting volume improvement effects.
💡Wait, this part is important!
When the CMC component is absorbed, you may feel a temporary reduction in volume. However, this is a natural process. Afterward, PCL will produce collagen, and the volume will fill up again.
If you are curious about more types of collagen boosters, you can check them through the link below.
👩🏻⚕️Summary of Gangnam Collagen Booster effects, prices, and how to avoid nodular side effects
What changes can you expect from the Ellanse effect?
1️⃣Improvement in volume and elasticity at once
You can expect both the effect of filling volume and improving skin elasticity simultaneously. Filling in the sunken areas can also help alleviate fine wrinkles.
2️⃣Becomes more natural over time
Since my skin produces collagen, the results tend to be closer to my skin texture rather than an artificially inflated feeling as time goes by.
3️⃣Relatively long-lasting
Regular hyaluronic acid fillers are known to last about a year. However, Ellanse can maintain its effects for 1-2 years or more, depending on the product type and individual condition.
4️⃣Expect more after 2-3 months
Collagen is not made overnight. After 2-3 months post-treatment, you can feel the skin texture becoming denser and the facial contours naturally getting refined.
Recommended for these individuals

Ellanse has relatively clear treatment areas.
✔️Forehead / Temples / Cheekbones / Cheeks / Nose / Nasolabial folds / Marionette lines / Jawline, etc.
Especially, it can help fill in areas that have sunken or sagged due to aging, aiding in contour improvement. However, remember that the area under the eyes requires careful consideration.
✔️Those who have tried fillers but were disappointed with the short duration
✔️Those who want volume but are also concerned about skin elasticity
✔️Those who desire natural results
✔️Those who want to fill in areas that have sagged due to aging
✔️Those who find it difficult to receive treatments frequently due to a busy lifestyle
Just keep this in mind!
As much as there are benefits, there are also things to be aware of in advance. Unlike hyaluronic acid fillers, Ellanse does not have a dissolving injection.
This means that if you are not satisfied after the treatment, it is not easy to reverse it immediately. Therefore, the initial planning stage of the treatment is very important, and sufficient consultation with experienced medical staff is essential.
Frequently Asked Questions
Q. How much does Ellanse cost per cc?
The total cost of Ellanse varies depending on the treatment area and the required cc, so it is difficult to provide a uniform amount. The exact price is best confirmed during a consultation regarding the desired area and volume. Derna is currently running various collagen booster events, including Ellanse.
If you are curious about the event prices, please check the page below.
🔎Go check the event prices for Ellanse (collagen booster)
※Events may change or end without notice. If you cannot find what you are looking for, please inquire for detailed guidance.
Q. What criteria should be used to determine the treatment area for Ellanse?
Ellanse is used to fill in areas that are sunken or sagging, such as the forehead, temples, cheekbones, cheeks, nose, nasolabial folds, marionette lines, and jawline. Since the required volume and skin thickness vary by area, the amount to be used in each area should be determined through diagnosis.
Q. I heard that the area under the eyes should be approached with caution. Why is Ellanse not recommended for the under-eye area?
The under-eye area has very thin skin, and if a high-density filler component is injected superficially, there is a relatively high risk of the Tyndall effect (bluish appearance) or uneven nodules. Therefore, for this area, we recommend using thinner and softer specialized fillers or other methods instead of Ellanse.
Q. I still have some hyaluronic acid filler left from a few months ago. Is it okay to inject Ellanse into that area right away?
Injecting Ellanse into a different layer while some existing filler remains is possible, but if the exact location and remaining amount are not assessed beforehand, it may result in excessive volume or uneven results. Therefore, it is safe to inform about the history of previous treatments during the consultation process and to proceed after checking the current condition.
Q. How long do swelling or bruising last after the treatment, and when can I return to work or wear makeup?
Minor bruising or swelling from needle marks may last for a few days, but most people can resume daily activities or light makeup without significant issues from the same day. However, if you have important schedules coming up, it is advisable to plan the treatment in advance, considering the recovery period.
Q. If there is no dissolving injection for Ellanse, how is treatment done if lumps or nodules form in the skin?
Since Ellanse does not have a dedicated dissolving enzyme like hyaluronic acid fillers, if nodules form, management is done through steroid injections, energy-based treatments like radiofrequency or laser, and massage to aid absorption. Since it is not easy to reverse immediately, it is crucial to have thorough consultations with experienced medical staff during the initial treatment planning stage.
Q. If I want to manage with lifting lasers like Ultherapy or Thermage, what order and how much interval should I maintain?
It is known that adding strong thermal energy like Ultherapy or Thermage during the period when Ellanse settles and collagen production progresses can affect the placement of ingredients or results, so it is common to maintain a certain interval between the two treatments. If you wish to combine them, it is advisable to consult with your doctor to determine the order and interval.
Q. After the maintenance period, is there no foreign substance left in the body, and is it safely excreted? When is it good to receive re-treatment?
The key ingredient of Ellanse, PCL, gradually breaks down and is excreted in the form of water and carbon dioxide over time. However, even after all the micro-particles are absorbed, the newly generated collagen structure remains, so the volume does not disappear abruptly in most cases. The timing for re-treatment should be determined through consultation while observing changes in facial condition as the maintenance period comes to an end.
Ellanse is not just a treatment that changes the current appearance but a procedure that creates long-term changes through the recovery of the skin structure itself. You can experience regaining your original face with the elasticity produced by your skin rather than forced volume.
If you are curious about the Ellanse treatment, please consult at Derna Clinic. Derna Clinic will be with you for your confidence to shine again.

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